Peptide Science & Research Portfolio
Comprehensive analytical guide detailing primary mechanisms of action, scientific research objectives, and standardized laboratory handling protocols for American Top Lab research compounds.
Retatrutide (Reta)
≥ 99.4% (RP-HPLC) 20mg Lyophilized Cake (2 Vials Pack) Metabolic / Tri-Agonist1. What It Does (Mechanism)
Engineered tri-agonist activating GIP, GLP-1, and Glucagon receptors concurrently. Elevates hepatic mitochondrial energy oxidation while suppressing metabolic intake signaling.
2. Why It Is Studied
- • Adiposity, metabolic kinetics, and hepatic lipid clearance models.
- • Thermogenic brown-fat and mitochondrial activation research.
- • Comparative tri-agonist vs dual-agonist receptor affinity studies.
3. Lab Preparation Protocol
Reconstitute using sterile Bacteriostatic Water (BAC) along the glass wall. Store reconstituted solution at 2°C – 8°C. Do not freeze once reconstituted.
Tirzepatide
≥ 99.2% (RP-HPLC) 15mg Lyophilized Cake Metabolic / Dual-Agonist1. What It Does (Mechanism)
Synthetic dual incretin peptide enhancing glucose-dependent insulin dynamics, gastric transit slowing, and central hypothalamic satiety modulation.
2. Why It Is Studied
- • Dual incretin receptor cooperativity and glycemic signaling cascades.
- • Pancreatic beta-cell cytoprotection in cellular stress models.
- • Cardiometabolic pathway biomarkers and lipid profiles.
3. Lab Preparation Protocol
Introduce diluent gently; swirl smoothly without foaming. Protect dry and reconstituted vials from direct UV light.
Semaglutide
≥ 99.5% (RP-HPLC) 5mg Lyophilized Cake Metabolic / Incretin1. What It Does (Mechanism)
Modified GLP-1 analog with Aib-8 substitution and hydrophilic spacer fatty diacid for high albumin binding affinity and extended in-vitro stability.
2. Why It Is Studied
- • Long-acting GLP-1 central nervous system signaling pathways.
- • Systemic vascular inflammation and endothelial markers.
- • Renal tissue cytoprotection in metabolic research assays.
3. Lab Preparation Protocol
Dissolve under aseptic laminar conditions. Preserve cold strictly at 2°C – 8°C.
BPC-157 (Pentadecapeptide)
≥ 99.7% (RP-HPLC) 10mg Lyophilized Cake Cytoprotective / Cellular Repair1. What It Does (Mechanism)
Stable 15-amino acid sequence that upregulates VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) and triggers the FAK-paxillin focal adhesion pathway.
2. Why It Is Studied
- • Tendon, ligament, and fibroblastic cellular migration assays.
- • Nitric oxide (NO) system modulation during acute tissue stress.
- • Gastrointestinal mucosal membrane integrity research.
3. Lab Preparation Protocol
Reconstitute with 1.0ml to 2.0ml BAC water. Lyophilized powder stable up to 36 months at -20°C or 24 months at 2°C – 8°C.
TB-500 (Thymosin Beta-4)
≥ 99.1% (RP-HPLC) 10mg Lyophilized Cake Cytoprotective / Tissue Remodeling1. What It Does (Mechanism)
Synthetic fraction of the actin-sequestering protein Thymosin Beta-4. Binds monomeric G-actin, accelerating endothelial migration and tissue remodeling.
2. Why It Is Studied
- • Endothelial cell recruitment and capillary formation assays.
- • Myofibrillar regeneration and skeletal fiber remodeling.
- • Reduction of acute oxidative stress and inflammation markers.
3. Lab Preparation Protocol
Slowly trickle bacteriostatic solvent; swirl gently until clear. Store cold at 2°C – 8°C.
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